Anabolic steroidsCochrane Database of Systematic Reviews: Plain Language Summaries [Internet]. Anabolic steroids include testosterone and its derivatives. One of the functions of testosterone is to help build muscle. Individuals with HIV infection anabolic steroids effects on hiv lose weight and have low anabolic steroids effects on hiv levels of testosterone; thus, the use of anabolic steroids in the treatment of weight loss in individuals with HIV infection may benefits of steroids for asthma beneficial. The purpose of this review was to evaluate anabolic steroids as a means of treatment of weight loss in individuals with HIV infection. The review includes 13 randomized clinical trials in the primary analysis.
Anabolic Steroids and HIV – PoWeR USA
The review covered 13 studies of adults age 24 to 42 with HIV, of whom received anabolic steroids for at least six weeks and of whom received placebo. The average weight increase in those taking anabolic steroids was nearly three pounds. The review appears in the most recent issue of The Cochrane Library , a publication of The Cochrane Collaboration, an international organization that evaluates medical research.
Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic. AIDS wasting, which leads to significant weight loss in people with HIV, causes severe loss of weight and muscle and can lead to muscle weakness, organ failure and shortened lifespan. Researchers have long sought to reverse this common, destructive effect of HIV with mixed success. Anabolic steroids are synthetic substances similar to the male sex hormone testosterone that promote growth of skeletal muscle and the development of male sexual characteristics.
Although most recently in the news for their misuse by professional athletes, anabolic steroids have legitimate medical application for men with low testosterone and people with certain types of anemia. Two anabolic steroids available in the United States, nandrolone decanoate and oxandrolone, have been used to help increase weight and muscle mass in small studies of people with wasting.
Conversely, anabolic steroid use has been associated with increased rates of HIV in those who share needles or use nonsterile needles when they inject steroids. In the review studies, anabolic steroids were administered to patients either orally or by injection.
The main side effects were mild and included abnormal liver function tests; acne; mild increase in body hair; breast tenderness; increased libido, aggressiveness and irritability; and mood swings — all common side effect of anabolic steroid use. If [testosterone] is in the low or low-normal range then a trial of [steroids] could be tried. The individual and the clinician should decide what result would constitute a successful trial: The reviews authors conclude that further studies are needed to determine if increase in weight leads to improved physical functioning and quality of life, and ultimately increased survival, as well as the potential for serious side effects, especially with prolonged use.
Cancel reply to comment. Parry outlines her research in diagnosing depression, which led to her winning the Pittcon Achievement Award. Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism.
Researchers develop new tool to protect against HIV infection. Researchers discover Tfh cell dysfunction in HIV-infected patients.
Resistance training enhances cellular recycling in muscle cells. Study identifies factors that lead to increased HIV testing among young adults. Research reveals new mechanism by which HIV evades the immune system. The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical. Post a new comment. Children with autism have gastrointestinal and immune system deregulation, research finds. Glucose metabolism is key to neural network development, finds study.
Flesh eating ulcer cases on the rise in Victoria. Intranasal spray shows promise for peanut allergy suppression. Early life stress impacts how the sensory systems develop, review shows. Validating the Diagnosis of Depression Prof.
Parry Hashemi Parry outlines her research in diagnosing depression, which led to her winning the Pittcon Achievement Award. Ann Smith Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism. Jasmohan Bajaj The microbiome is the collection of microorganisms that colonize the human body. What is a Baker's Cyst?
Health Effects of a Gluten Free Diet. Researchers present case study of management of rheumatic mitral regurgitation in woman contemplating pregnancy. Tradeshow Talks with FarmaTrust. Teen patient gets a new lease on life. Newsletters you may be interested in. Dermatology Subscribe or Preview. Hematology Subscribe or Preview. You might also like Former California state contractor sued over breach of HIV patient privacy.