16 Ways to Fight GynecomastiaJuly 14, 23 Comments. Most people think the only viet keto diet steroidology combat gyno is to use Nolvadex or Clomid. In this article I summarize alternative methods for combating the occurrence of gyno. The advice given in this article is the result of over 10 years experience in counseling individuals with AAS induced gyno. If you keto diet steroidology gyno as a result of an endocrine disorder, I advise consulting your doctor before making changes to your prescribed medical regimen.
16 Ways to Fight Gynecomastia | androseries
July 14, 23 Comments. Most people think the only way to combat gyno is to use Nolvadex or Clomid. In this article I summarize alternative methods for combating the occurrence of gyno. The advice given in this article is the result of over 10 years experience in counseling individuals with AAS induced gyno.
If you have gyno as a result of an endocrine disorder, I advise consulting your doctor before making changes to your prescribed medical regimen. During mammary tissue growth the onset of gyno , you may notice the following symptoms —. I promise — that is the last time I will ever say nipples. Remember, it is normal to have a small flat pea sized lump under the nipple.
This is NOT gyno. Now, if you allow these above symptoms to progress for several weeks then you may develop gyno. Mammary tissue gyno can be catabolized like any other tissue in the body. This type of gyno can transform into a more serious level 2 gyno if left untreated for more than weeks. In most cases, this initial level 1 gyno disappears once the hormonal environment improves, which is generally weeks after the inflicting steroids clear the system.
Level 2 — A quarter sized glandular lump. Completely reversing level 2 gyno requires aggressive dietary and supplemental intervention in conjunction with prescription grade drugs. Be warned, if gyno is allowed to grow large enough, the cost of surgery may be more cost efficient than trying to battle the gyno through drug and lifestyle changes — which could otherwise take months or years of intervention.
Consider all the following points. Remember, there are many factors that can contribute to gyno and performing just a handful of the points below may be the key to avoiding gyno all together. Your naturally occurring 5a-reduced metabolites are your friends in preventing and reversing gyno. These hormones help prevent gyno by lowering estrogen and blocking the effect of estrogen at the hormone receptor.
If you are concerned about gyno, avoid finesteride at all costs. It lowers all 5a-reduced metabolites to undesirable levels and has an extremely long half-life which continues to suppress DHT levels long after discontinuing the drug.
Plus, progesterone can clear the system within 24hrs making a mistake in dosing much less risky. Almost all sources of gyno can be linked back to having insufficient levels of 5a-reduced metabolites in the body. Trenbolone, TREN, Nandrolone can cause gyno because they lack a potent 5a-reduced metabolite dihydro nandrolone is weaker than dihydro testosterone. This can avoid most if not all of the gyno problems associated with progestational hormones. It is the antagonistic action of 5a-reduced hormones that is required.
While DHT derivatives or analogs such as Anavar, Winstrol, Masteron, Epistane, Superdrone, ect may be 5a-reduced, they cannot convert to actual DHT and thus cannot directly inhibit gyno at the receptor level since they lack the ultra-high binding affinity for the AR that true DHT possesses.
Natural anti-estrogens resveratrol, chrysin, I3C, DIM, ect are great for PCT and can stimulate the HPTA and manage healthy estrogen metabolism, but they are not strong enough to prevent aromatization from high doses of aromatizing steroids. Reducing prolactin will reduce the overall stimulation on mammary growth. Suppressing prolactin is useful as a temporary method to help slow or stop gyno growth.
However, continuing anti-prolactin treatment is not recommended to be continued beyond 8 weeks. Methods of suppressing prolactin include —.
This increases prolactin release which can make gyno worse. IGF-1, GH, insulin and prolactin are all potent growth factors in gyno growth. Limiting these hormones will reduce the likelihood of experiencing gyno symptoms. Cutting calories especially carbohydrates will suppress insulin and IGF-1 therefore reducing the overall stimulatory effect on mammary growth. Body fat adipose tissue is the main site for androgens to convert to estrogens. Therefore, being overweight or having high body fat increases your gyno risk.
This is another good reason to go on a cutting cycle if you are gyno prone. Reducing body fat will lower your rate of estrogen conversion from aromatizing steroids. Caffeine consumption can inhibit clearance of estrogen from the liver by competing for the P oxidase system. Avoid caffeine if you are concerned about high estrogen levels. Avoid supplements containing forskolin if concerned about gyno.
Forskolin increases aromatase activity via cAMP modulation and can increase formation of estrogen. Increasing fiber intake both soluble and insoluble can enhance clearance of estrogens from the intestines. Reducing estrogen below the normal range such as over dosing arimidex, letrozol, aromasin or formestane can eventually reduce SHBG levels, thus allowing more estrogen to freely circulate by offsetting it from SHBG. Higher levels of freely circulating estrogen can amplify breast tissue growth SHBG also appears to have anti-estrogenic effects at the cell receptor level.
People have a tendency to panic at the first sign of gyno and drop everything. Generally, just lowering the dose of the afflicting steroid can offer gyno relief within days. You do not need a SERM tormifene, clomid or nolva to avoid gyno from a properly planned cycle. If you are still having gyno problems after following the above points, consider the fact that you have a poorly planned cycle and you need to revaluate the compounds you have chosen.
Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse. Lund TD, et al. Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor. Szelei J, et al. The non-aromatizable androgen, dihydrotestosterone, induces antiestrogenic responses in the rainbow trout.
Shilling AD, et al. The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus. Steroid modulation of aromatase activity in human cultured breast carcinoma cells. Perel E, et al. Aromatase activity in the breast and other peripheral tissues and its therapeutic regulation. Killinger DW, et al. The intracellular control of aromatase activity by 5 alpha-reduced androgens in human breast carcinoma cells in culture.
FSH-induced aromatase activity in porcine granulosa cells: Chan WK, et al J Endocrinol. The effect of 5 alpha-reductase inhibitors on erectile function. Canguven O, Burnett AL. Journal of Clinical Endocrinology and Metabolism Vol. Successful percutaneous dihydrotestosterone treatment of gynecomastia occurring during highly active antiretroviral therapy: Benveniste O et al.
Kuhn J et al. Percutaneous dihydrotestosterone DHT treatment. Nieschlag E, Behre HM, eds. Metabolism and receptor binding of nandrolone and testosterone under invitro and invivo conditions. Acta Endocrinol Suppl Copenh. Pharmacology of Reproduction David E, et al. Principles of Pharmacology second edition p. Antagonism of estrogen-induced prolactin release by dihydrotestosterone.
Brann DW, et al. Dietary fiber intake and endogenous serum hormone levels in naturally postmenopausal Mexican American women: Monroe KR et al. Williams Textbook of Endocrinology. Sex steroid binding protein receptor SBP-R is related to a reduced proliferation rate in human breast cancer. Catalano MG, et al. Breast Cancer Res Treat. Biological relevance of the interaction between sex steroid binding protein and its specific receptor of MCF-7 cells under SBP and estradiol treatment. Fissore F, et al.
Progestin-dependent effect of forskolin on human endometrial aromatase activity. Forskolin up-regulates aromatase CYP19 activity and gene transcripts in the human adrenocortical carcinoma cell line HR. Watanabe M, Nakajin S. Prolactin Gyno or good ol' fashion Estro? Lactating after test only cycle [Forums].
Aromasin, Primo, Gyno, Test Gyno from 1-andro rx [Forums]. Quick question about gyno [Forums]. The tits of a bitch [Forums]. This is a very informative post.